Inclusion of 1,4-bis(diphenylhydroxymethyl)benzene with amides: structure and selectivity

Abstract

The host compound 1,4-bis(diphenylhydroxymethyl)benzene is shown to include a series of amides: N, N-dimethylacetamide (DMA), N,N-dimethylformamide (DMF), N-methylacetamide (NMA) and Nmethylformamide (NMF). The resultant inclusion compounds were characterised using thermal analysis and single crystal X-ray diffraction. A kinetic experiment was performed on the DMF clathrate and the activation energy determined. The host selectivity for the amides was studied through competition experiments.