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http://hdl.handle.net/11189/7627| Title: | Synthesis of fluorescent CuInS2/ZnS quantum dots—porphyrin conjugates for photodynamic therapy | Authors: | Tsolekile, Ncediwe Ncapayi, Vuyelwa Parani, Sundararajan Sakho, El Hadji Mamour Matoetoe, Mangaka Songca, Sandile P Oluwafemi, Oluwatobi S |
Keywords: | Porphyrins;photodynamic therapy (PDT);CuInS2/ZnS ternary quantum dots;oxygen generation;insolubility | Issue Date: | 2018 | Publisher: | Cambridge University Press | Source: | Tsolekile, N., Ncapayi, V., Parani, S. et al. 2018. Synthesis of fluorescent CuInS2/ZnS quantum dots—porphyrin conjugates for photodynamic therapy. MRS Communications, 8(2): 398–403. [http://doi.org/10.1557/mrc.2018.60] | Journal: | MRS Communications | Abstract: | Porphyrins are photosensitisers used in photodynamic therapy (PDT) due to their tumor localization and in situ singlet oxygen generation. However, their limited absorption, insolubility, and aggregation in an aqueous medium limited their effective application in PDT. To overcome these limitations, we herein, report a large-scale aqueous synthesis of CuInS2/ZnS ternary quantum dots, and its conjugation to 5, 10, 15, 20- meso(4-hydroxyphenyl) porphyrin. The singlet oxygen generation of this highly aqueous soluble novel conjugate shows its potential for PDT applications. | URI: | http://hdl.handle.net/11189/7627 | ISSN: | 2159-6867 2159-6859 |
DOI: | http://doi.org/10.1557/mrc.2018.60 |
| Appears in Collections: | Appsc - Journal Articles (DHET subsidised) |
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| File | Description | Size | Format | |
|---|---|---|---|---|
| Synthesis of fluorescent CuInS2-ZnS quantum dots.pdf | 1.45 MB | Adobe PDF | View/Open |
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