Please use this identifier to cite or link to this item:
Title: Health benefits of a natural carotenoid rich oil: a proposed mechanism of protection against ischaemia/ reperfusion injury
Authors: Van Rooyen, Jacques 
Esterhuyse, Adriaan J 
Engelbrecht, Anna-Mart 
Du Toit, Eugene F. 
Keywords: Anti-oxidant rich oil;carotenoid;tocotrienol;tocopherol;red palm oil;oxidative stress;ischaemia/reperfusion
Issue Date: 2008
Publisher: Wiley
Source: Van Rooyen, J., Esterhuyse, A. J., Engelbrecht, A. et al. 2008. Health benefits of a natural carotenoid rich oil: a proposed mechanism of protection against ischaemia/ reperfusion injury. Asia Pacific Journal of Clinical Nutrition, 17(S1): 316-319. []
Journal: Asia Pacific Journal of Clinical Nutrition 
Abstract: Numerous studies have reported the protective properties of carotenoid supplementation against skin and eye as- sociated diseases. However, conflicting data concerning the efficacy of -carotene in the pathogenesis of cancers and cardiovascular disease exist. It has been shown that β-carotene is an effective antioxidant on its own or in combination with other antioxidants. Red palm oil (RPO) is a potent anti-oxidant rich oil which consists of caro- tenoids, tocopherols, tocotrienols and lycopenes as well as lipid fractions such as squalene, saturated and unsatu- rated fatty acids (which maximize absorption of these anti-oxidants) and Co-enzyme Q10. and -carotene ac- count for more than 90% of the total carotene in RPO. It is known that ischaemia/reperfusion-induced injury causes an imbalance in oxygen supply which can lead to oxidative stress in the heart. It has been shown that the mitogen-activated protein kinases (MAPKs), PKB/Akt and the NO-cGMP all play vital roles in ischae- mia/reperfusion injury in the heart. Therefore, our review mainly focuses on the signaling pathways involved in functional recovery induced by a natural carotenoid oil after ischaemia/reperfusion injury
ISSN: 1440-6047
Appears in Collections:HWSci - Journal Articles (DHET subsidised)

Files in This Item:
File Description SizeFormat 
Health benefits of a natural carotenoid rich oil.pdf151.32 kBAdobe PDFView/Open
Show full item record

Page view(s)

checked on Feb 9, 2021


checked on Feb 9, 2021

Google ScholarTM


Items in Digital Knowledge are protected by copyright, with all rights reserved, unless otherwise indicated.