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Title: Natural occurrence of some fusarium mycotoxins in corn from low and high esophageal cancer prevalence areas of the Transkei, Southern Africa
Authors: Sydenham, Eric W. 
Thiel, PG 
Marasas, Walter F.O 
Shephard, Gordon Seymour 
Van Schalkwyk, Dirk J 
Koch, Klaus R 
Keywords: Esophageal cancer;Transkei;Southern Africa;Moldy corn;Fusarium mycotoxins
Issue Date: 1990
Publisher: Journal of Agricultural and Food Chemistry
Abstract: Moldy and healthy corn samples were collected from two opposing human esophageal cancer prevalence areas of the Transkei, southern Africa, during 1985, and screened mycologically. The moldy corn samples were analyzed for the presence of several Fusarium mycotoxins, including deoxynivalenol (DON), diacetoxyscirpenol (DAS), moniliformin (MON), nivalenol (NIV), T-2 toxin, zearalenone (ZEA), fumonisins BI (FBI) and Bz (FBz), and tricarballylic acid [(TCA), a compound present in the structures of the fumonisins]. The healthy corn samples were screened for the presence of FBI and FBz. High concentrations of DON, MON, NIV, ZEA, FBI, and FBz were recorded in the moldy corn samples. Statistical correlations between the incidence of Fusarium species and mycotoxin levels, present in the corn samples, agreed with the toxin-producing abilities of the individual Fusarium species. Additional data clearly indicated that significantly higher levels of both FBI and FBz were present in the healthy corn samples from the high esophageal cancer rate area than in corresponding samples from the lowrate area.
ISSN: 0021-8561
Appears in Collections:HWSci - Journal Articles (DHET subsidised)

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