Please use this identifier to cite or link to this item: http://hdl.handle.net/11189/4535
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dc.contributor.authorBatisa, Eustina-
dc.contributor.authorAyamine, Alban-
dc.contributor.authorKilinkissa, Ornella EY-
dc.contributor.authorBáthori, Nikoletta B-
dc.date.accessioned2016-07-11T13:07:30Z-
dc.date.available2016-07-11T13:07:30Z-
dc.date.issued2014-
dc.identifier.citationCrystEngComm, 2014, 16, 9992en_US
dc.identifier.urihttp://dx.doi.org/10.1039/c4ce01298d-
dc.identifier.urihttp://hdl.handle.net/11189/4535-
dc.description.abstractThis study investigates the relationships between the supramolecular structure and the solubility and melting point of six multicomponent crystals involving fumaric acid (FUM series) and adipic acid (ADI series). The crystals were prepared by solvent evaporation and fully characterised by thermal and diffraction techniques. In each series the melting points of the multicomponent crystals are lower than the relevant carboxylic acid and they show partial correlation with their aqueous solubilities. With the aid of Hirshfeld surface analysis, the relationships between solubility, melting point and the supramolecular structure are discussed.en_US
dc.description.sponsorshipNational Research Foundation of South Africa and the Cape Peninsula University of Technology.en_US
dc.language.isoenen_US
dc.publisherCrystEngCommen_US
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/3.0/za/en
dc.subjectMulticomponent crystalsen_US
dc.subjectFumaric aciden_US
dc.subjectAdipic aciden_US
dc.subjectCocrystallisationen_US
dc.subjectPharmaceutical cocrystalsen_US
dc.titleMelting point–solubility–structure correlations in multicomponent crystals containing fumaric or adipic aciden_US
dc.type.patentArticleen_US
Appears in Collections:Appsc - Journal Articles (DHET subsidised)
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