Please use this identifier to cite or link to this item: http://hdl.handle.net/11189/3400
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dc.contributor.authorJacobs, Ayesha-
dc.contributor.authorNoa, Francoise M. Amombo-
dc.contributor.authorTaljaard, Jana H.-
dc.contributor.authorFrancoise, Mystereen_US
dc.date.accessioned2015-12-07T06:16:23Z-
dc.date.available2015-12-07T06:16:23Z-
dc.date.issued2013-
dc.identifier.citationJacobs, A., Noa, F.M.A. & Taljaard, J.H. 2013. Co-crystals of 9-(2-Methoxyphenyl)-9H-xanthen-9-ol with Caffeine and Theophylline. Journal of Chemical Crystallography, 43(10): 554-560. [https://link.springer.com/article/10.1007/s10870-013-0457-3]en_US
dc.identifier.issn1074-1542-
dc.identifier.issn1572-8854-
dc.identifier.urihttp://dx.doi.org/10.1007/s10870-013-0457-3-
dc.identifier.urihttp://hdl.handle.net/11189/3400-
dc.descriptionJacobs, A., Noa, F.M.A. & Taljaard, J.H. (2013). Co-crystals of 9-(2-Methoxyphenyl)-9H-xanthen-9-ol with Caffeine and Theophylline. Journal of Chemical Crystallography, 43(10): 554-560. http://dx.doi.org/10.1007/s10870-013-0457-3en_US
dc.description.abstractThe host compound 9-(2-methoxyphenyl)-9H-xanthen-9-ol (H) forms a 2:1 co-crystal with caffeine (2H·CAF). The structure was solved successfully in the triclinic space group P-1 with unit cell dimensions: a = 9.1747(8) Å, b = 13.7910(12) Å, c = 16.7207(14) Å, α = 107.036(2)°, β = 99.213(2)° and γ = 95.812(2)°. The structure of the apohost was also solved in P-1 with unit cell dimensions: a = 11.402(2) Å, b = 11.993(2) Å, c = 12.994(3) Å, α = 64.96(3)°, β = 73.29(3)° and γ = 74.89(3)°. The co-crystal hydrate of H with theophylline, 2H·THEO·½H 2 O, crystallised in the space group P21/c, unit cell dimensions: a = 13.8121(12) Å, b = 14.7391(13) Å, c = 20.4630(18) Å, β = 106.759(2)°. Graphical Abstract A co-crystal of 9-(2-methoxyphenyl)-9H-xanthen-9-ol and caffeine (2H·CAF) is stabilized by hydrogen bonding to the imidazole nitrogen and the amide oxygen of caffeine.en_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/3.0/za/en
dc.subjectCaffeineen_US
dc.subjectTheophyllineen_US
dc.subjectXanthenol hosten_US
dc.subjectCo-crystalen_US
dc.titleCo-crystals of 9-(2-Methoxyphenyl)-9H-xanthen-9-ol with Caffeine and Theophyllineen_US
dc.type.patentArticleen_US
Appears in Collections:Appsc - Journal Articles (DHET subsidised)
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