Louw, Roan

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Issue DateTitleAuthor(s)
12025A standardised exercise protocol to induce oxidative stress in humans: validation with a dietary polyphenol interventionKamati, Oiva ; Bragagna, Laura ; Bester, Dirk ; Wagner, Karl-Heinz ; Stürmer, Vera ; Gassner, Markus ; Maqboul, Lina ; Louw, Roan ; West, Sacha ; Davies, Simeon ; Marnewick, Jeanine L 

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Full Name
Louw, Roan
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R.
 
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ORCID
Biography
I am currently Professor of Biochemistry and Research Director: Human Metabolomics at the North-West University (NWU), Potchefstroom Campus in South Africa. This biographical information is structured to describe my involvement in (1) research and post-graduate training, (2) teaching and learning, (3) community engagement and (4) management. 1) RESEARCH AND POST-GRADUATE TRAINING My research background is on the involvement of the mitochondrion in health and disease and can be summarized as (1) metabolomics and cellular adaptations of mitochondrial energy deficiencies, (2) identification and characterization of inherited mitochondrial disorders in the South African population and (3) the involvement of energy metabolism in non-communicable disease (cardiovascular disease) and infectious disease (HIV). My outputs include 50 publications, while my papers were cited 926 times (Google Scholar, 03/01/2022). I have published with many of the leaders in my field, including the groups from Nijmegen (Prof Jan Smeitink and Prof Ron Wevers), Helsinki (Prof Anu Suomalainen), Newcastle (Prof Sir Doug Turnbull) and Gent (Prof Rudy van Coster). My papers have been cited by leading experts in my field, including Professors DC Wallace, DM Turnbull, DR Thorburn and RJA Wanders. I have trained 48 post-graduate students and contributed to 61 conference proceedings and colloquia. I actively collaborate with leading researchers in my field investigating the cellular responses of mitochondrial disease. Over the past 17 years I have obtained research funding as primary investigator/co-applicant in excess of ZAR 30.3 million (∼USD 2.24 million) and currently hold a C3 NRF rating (established researcher) with the National Research Foundation of South Africa. I am also a registered Medical Scientist at the Health Professions Council of South Africa (HPCSA) in order to do diagnostic work on mitochondrial disease. My outputs (papers, conferences and post-graduate students delivered) as well as the citing of my papers by experts in the field demonstrate that I do receive considerable national and international recognition for the quality and impact of my work. 2) TEACHING AND LEARNING I have been actively involved in teaching and learning since 2006. Over the years I was responsible for lecturing, study material selection, course design and development as well as student examinations / evaluation of 1st year BSc to BSc Honours (4th year) students. I received an average of 86 % for my student evaluations over the past 3 years. The average pass rate of all my courses was 84 % over the period, well above the norm. 3) COMMUNITY ENGAGEMENT I have 21 years’ experience diagnosing mitochondrial disease in South Africa. Along with my colleague (Prof van der Westhuizen), we manage the only laboratory in South Africa diagnosing mitochondrial disease on enzyme level in muscle biopsies (Mitochondria Research Laboratory - http://natural-sciences.nwu.ac.za/focus-area-human-metabolomics/mitochondria-laboratory). For this work I am registered as a Medical Scientist at the Health Professions Council of South Africa (HPCSA). I am also actively involved in the marketing of the Biochemistry Subject Group (Department) to school children through the annual NWU open day as well as the Science, Engineering, Technology and Health (SETH) academy. 4) MANAGEMENT I served in numerous management positions at the North-West University (NWU), including Subject Head for Biochemistry (equivalent to Head of Department) and Deputy School Director (acting) for the School for Physical and Chemical Sciences. Currently I am the Research Director: Human Metabolomics. I am also a member of the NWU Senate and serve on the Editorial Board of Metabolomics as well as on the Industry Engagement Subcommittee of the Metabolomics South Africa Board.
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