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Title: Tumor necrosis factor is critical to control tuberculosis infection
Authors: Jacobs, Muazzam 
Togbe, Dieudonnée 
Fremond, Cecile 
Samarina, Arina 
Allie, Nasiema 
Botha, Tania 
Carlos, Daniela 
Parida, Shreemanta K. 
Grivennikov, Sergei 
Nedospasov, Sergei 
Monteiro, Analbery 
Le Bert, Marc 
Quesniaux, Valerie 
Ryffel, Bernhard 
Keywords: Tumor necrosis factor;Tuberculosis;Reactivation of infection;Gene deficient mice
Issue Date: 2007
Publisher: Elsevier
Source: Jacobs, M., Togbe, D., Fremond, C. et al. 2007. Tumor necrosis factor is critical to control tuberculosis infection. Microbes and Infection, 9: 623-628. []
Journal: Microbes and Infection 
Abstract: Tumor necrosis factor (TNF) is critical and non-redundant to control Mycobacterium tuberculosis infection and cannot be replaced by other proinflammatory cytokines. Overproduction of TNF may cause immunopathology, while TNF neutralization reactivates latent and chronic, controlled infection, which is relevant for the use of neutralizing TNF therapies in patients with rheumatoid arthritis.
ISSN: 1286-4579
Appears in Collections:HWSci - Journal Articles (DHET subsidised)

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