Please use this identifier to cite or link to this item: http://hdl.handle.net/11189/5799
Title: Recent developments in polyfluoroalkyl compounds research: A focus on human/environmental health impact, suggested substitutes and removal strategies
Authors: Mudumbi, JBN 
Ntwampe, Seteno KO 
Matsha, T 
Mekuto, L 
Itoba-Tombo, EF 
Keywords: Antimicrobial compounds;Inhibitory activity;Antimicrobial quantification;Candida pyralidae
Issue Date: 2017
Publisher: Environmental Monitoring and Assessment
Source: Mudumbi, J.B.N., Ntwampe, S.K.O., Matsha, T., Mekuto, L. & Itoba-Tombo, E.F., 2017. Recent developments in polyfluoroalkyl compounds research: A focus on human/environmental health impact, suggested substitutes and removal strategies. Environmental Monitoring and Assessment
Abstract: Between the late 1940s and early 1950s, humans manufactured polyfluoroalkyl compounds (PFCs) using electrochemical fluorination and telomerisation technologies, whereby hydrogen atoms are substituted by fluorine atoms, thus, conferring unnatural and unique physicochemical properties to these compounds. Presently, there are wide ranges of PFCs and, owing to their bioaccumulative properties; they have been detected in various environmental matrices and in human sera. It has thus been suggested that they are hazardous. Hence, this review aims at highlighting the recent development in PFC research, with a particular focus on perfluorooctanoate (PFOA) and perfluorooctane sulfonate (PFOS), the most studied and predominantly found PFC in various environmental matrices, although recent reports have included perfluorobutane sulfonate (PFBS), which was previously regarded as innocuously harmless, when compared to its counterparts, PFOA and PFOS. As such, proper investigations are thus required for a better understanding of short-chain PFC substitutes, which have been suggested as suitable replacements to long-chained PFCs, although these substitutes have also been suggested to pose various health risks comparable to those associated with long-chain PFCs. Similarly, several novel technologies, such as PFC reduction using Zero Valent Iron, including removal at point of use, have been proposed.
URI: http://hdl.handle.net/11189/5799
Appears in Collections:BioERG - Books / Book Chapters

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