Please use this identifier to cite or link to this item: http://hdl.handle.net/11189/4535
Title: Melting point–solubility–structure correlations in multicomponent crystals containing fumaric or adipic acid
Authors: Batisa, Eustina 
Ayamine, Alban 
Kilinkissa, Ornella EY 
Báthori, Nikoletta B 
Keywords: Multicomponent crystals;Fumaric acid;Adipic acid;Cocrystallisation;Pharmaceutical cocrystals
Issue Date: 2014
Publisher: CrystEngComm
Source: CrystEngComm, 2014, 16, 9992
Abstract: This study investigates the relationships between the supramolecular structure and the solubility and melting point of six multicomponent crystals involving fumaric acid (FUM series) and adipic acid (ADI series). The crystals were prepared by solvent evaporation and fully characterised by thermal and diffraction techniques. In each series the melting points of the multicomponent crystals are lower than the relevant carboxylic acid and they show partial correlation with their aqueous solubilities. With the aid of Hirshfeld surface analysis, the relationships between solubility, melting point and the supramolecular structure are discussed.
URI: http://dx.doi.org/10.1039/c4ce01298d
http://hdl.handle.net/11189/4535
Appears in Collections:Appsc - Journal Articles (DHET subsidised)

Files in This Item:
File Description SizeFormat 
Batisa_Eustina_Ayamine_Alban_Kilinkissa_Ornella _E _Y_ Báthori_Nikoletta _B_AppSci_2014.pdfMain article3.95 MBAdobe PDFView/Open
Show full item record

Page view(s)

32
Last Week
0
Last month
0
checked on Feb 9, 2021

Download(s)

47
checked on Feb 9, 2021

Google ScholarTM

Check


This item is licensed under a Creative Commons License Creative Commons