Please use this identifier to cite or link to this item: http://hdl.handle.net/11189/4463
Title: Development and evaluation of a sensitive Mycotoxin Risk Assessment Model (MYCORAM)
Authors: Burger, Hester-Mari 
Lombard, Martani J 
Shephard, Gordon S 
Danster-Christians, Natasha 
Gelderblom, Wentzel CA 
Keywords: Mycotoxins exposure;Probable daily intakes;Maize consumers;Risk assessment model;South Africa
Issue Date: 2014
Publisher: Toxicological Sciences
Abstract: The differential risk of exposure to fumonisin (FB), deoxynivalenol (DON), and zearalenone (ZEA) mycotoxins to the South African population, residing in the nine Provinces was assessed during a cross-sectional grain consumer survey. The relative per capita maize intake (g/day) was stratified by gender, ethnicity, and Province and the probable daily intake (PDI) for each mycotoxin (ng/kg body weight/day) calculated utilizing SPECIAL and SUPER dry milled maize fractions representing different exposure scenarios. Men consumed on an average more maize (173 g/day) than women (142 g/day) whereas the black African ethnic group had the highest intake (279 g/day) followed by the Colored group (169 g/day) with the Asian/Indian and White groups consuming lower quantities of 101 and 80 g/day, respectively. The estimated mean PDIs for the various subgroups and Provinces, utilizing the different dry milled maize fractions, were below the provisional maximum tolerable daily intake (PMTDI) for each mycotoxin. A distinct and more sensitive mycotoxin risk assessment model (MYCORAM) for exposure, stratified by Province and ethnicity were developed utilizing specific maize intake increments (g/kg body weight/day) that provides information on the percentage of the population exposed above the PMTDI for each mycotoxin.
URI: http://dx.doi.org/doi:10.1093/toxsci/kfu134
http://hdl.handle.net/11189/4463
Appears in Collections:Appsc - Journal Articles (DHET subsidised)

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