Please use this identifier to cite or link to this item: http://hdl.handle.net/11189/2718
Title: Optimal waist-to-height ratio values for cardiometabolic risk screening in an ethnically diverse sample of South African urban and rural school boys and girls
Authors: Matsha, Tandi E 
Kengne, Andre-Pascal 
Yako, Yandiswa Y 
Hon, Gloudina M 
Hassan, Mogamat Shafick 
Erasmus, Rajiv T 
Issue Date: 2013
Source: Matsha, T. E., Kengne, A. P., Yako, Y. Y., Hon, G. M., Hassan, M. S., & Erasmus, R. T. (2013). Optimal waist-to-height ratio values for cardiometabolic risk screening in an ethnically diverse sample of South African urban and rural school boys and girls. PloS one, 8(8), e71133.
Abstract: Background The proposed waist-to-height ratio (WHtR) cut-off of 0.5 is less optimal for cardiometabolic risk screening in children in many settings. The purpose of this study was to determine the optimal WHtR for children from South Africa, and investigate variations by gender, ethnicity and residence in the achieved value. Methods Metabolic syndrome (MetS) components were measured in 1272 randomly selected learners, aged 10–16 years, comprising of 446 black Africans, 696 mixed-ancestry and 130 Caucasians. The Youden’s index and the closest-top-left (CTL) point approaches were used to derive WHtR cut-offs for diagnosing any two MetS components, excluding the waist circumference. Results The two approaches yielded similar cut-off in girls, 0.465 (sensitivity 50.0, specificity 69.5), but two different values in boys, 0.455 (42.9, 88.4) and 0.425 (60.3, 67.7) based on the Youden’s index and the CTL point, respectively. Furthermore, WHtR cut-off values derived differed substantially amongst the regions and ethnic groups investigated, whereby the highest cut-off was observed in semi-rural and white children, respectively, Youden’s index0.505 (31.6, 87.1) and CTL point 0.475 (44.4, 75.9). Conclusion The WHtR cut-off of 0.5 is less accurate for screening cardiovascular risk in South African children. The optimal value in this setting is likely gender and ethnicity-specific and sensitive to urbanization.
URI: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0071133
http://hdl.handle.net/11189/2718
ISSN: 1932-6203
Appears in Collections:HWSci - Journal Articles (DHET subsidised)
Prof. Thandi Matsha

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