Please use this identifier to cite or link to this item: http://hdl.handle.net/11189/2714
Title: The role of red blood cells in enhancing or preventing HIV infection and other diseases
Authors: Motswaledi, Modisa S 
Kasvosve, Ishmael 
Oguntibeju, Oluwafemi Omoniyi 
Issue Date: 2013
Source: Motswaledi, M. S., Kasvosve, I., & Oguntibeju, O. O. (2013). The Role of Red Blood Cells in Enhancing or Preventing HIV Infection and Other Diseases. BioMed research international, 2013.
Abstract: Aim. To highlight the apparently neglected role of erythrocyte antigens in the epidemiology of infectious diseases, especially HIV, with the prime objective of stimulating research in this area. Method. A literature search was performed on the PubMed for relevant papers from 1984 to 2013, the era covering active HIV research. This was achieved by using the phrases “erythrocyte blood groups HIV” (81 papers) or “red cell antigen, blood groups, and HIV” (60 papers). A manual Google Scholar search was done and supplemented by original papers referenced by various authors. However, the review was limited by the relative scarcity of papers on the subject, and only papers written in English were reviewed during the period October 2012 to September 2013. Results.Many communicable and noncommunicable diseases are associated with specific blood groups. Examples of these diseases are discussed in detail.HIV has been shown to bind to erythrocytes, and candidate erythrocyte-bindingmolecules andmechanisms are also discussed. Moreover, erythrocyte-HIV binding is associated with increased viral infectivity, thus, underscoring the need to study this phenomenon and its implications for HIV epidemiology. Conclusion. Erythrocyte antigens may be important in the pathogenesis and epidemiology of many diseases, including HIV.
URI: http://dx.doi.org/10.1155/2013/758682
http://hdl.handle.net/11189/2714
ISSN: 2314-6133
Appears in Collections:HWSci - Journal Articles (DHET subsidised)

Files in This Item:
File Description SizeFormat 
Motswaledi_Modisa_S_Kasvosve_Ishmael_Oguntibeju_Oluwafemi_O_Health & Well_2013.pdfMain Article1.16 MBAdobe PDFView/Open
Show full item record

Page view(s)

16
Last Week
0
Last month
1
checked on Nov 16, 2018

Download(s)

7
checked on Nov 16, 2018

Google ScholarTM

Check


Items in Digital Knowledge are protected by copyright, with all rights reserved, unless otherwise indicated.