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Title: Overview of parameters influencing biomass and bioreactor performance used for extracellular ligninase production from phanerochaete chrysosporium
Authors: Ntwampe, Seteno Karabo Obed 
Chowdhury, Faysol 
Sheldon, Marshall Sheerene 
Volschenk, Heinrich 
Keywords: Phanerochaete chrysosporium;Lignin peroxidase;Manganese peroxidase;Dissolved oxygen;Bioreactors
Issue Date: Sep-2010
Publisher: Technology Institute of ParanĂ¡ - Tecpar
Source: Vol.53, n. 5: pp.1057-1066, September-October 2010
Abstract: The production of extracellular enzymes is gaining momentum as commercial interests seek alternative ways to improve the productivity in the biotechnology and pharmaceutical industries. Early research studies looked at improving batch bioreactor operational challenges; however, the use of continuous cultures was indicated to be favourable. This led to a new approach developed to produce extracellular enzymes continuously using fixed-film bioreactors from biofilms immobilised on polymeric and inorganic membranes. In this review, the performance of P. chrysosporium biomass, evaluated in terms of ligninase production using different bioreactor operation conditions, is highlighted. Furthermore, the limitations related to the implementation of optimised batch culture conditions to continuous fixed-film bioreactors are discussed. DO transportation, trace element toxicity and lipid peroxidation effects on P. chrysosporium biomass in fixed-film bioreactors operated for elongated periods, are also discussed.
ISSN: 1516-8913
Appears in Collections:Eng - Journal Articles, Faculty of Engineering
Prof. Seteno Karabo Ntwampe

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